Áreas de investigación

Unidad de Investigación Traslacional

La Unidad de Investigación Traslacional es un grupo de investigadores de alto desempeño a nivel nacional e internacional, que fortalecen la producción científica de Médica Sur en un ambiente de colaboración y trabajo en equipo, a través de colaboración interna y externa.

La Unidad de Investigación Traslacional está comprometida con el desarrollo de investigadores capaces de innovar y trascender en la investigación básica, clínica y epidemiológica, brindando las herramientas necesarias que permitan desarrollar proyectos de investigación innovadores, aplicando la bioética y adecuados diseños metodológicos.

Misión: Desarrollar un espacio adecuado para realizar investigación traslacional involucrando diversos niveles académicos y especialidades de ciencias de la salud, de tal forma que puedan consolidarse diferentes líneas de investigación.

Visión: Ser un centro y referente de investigación traslacional con grupos líderes de investigación y formación de recursos humanos con la capacidad de innovar y mejorar diagnóstico y tratamiento de los principales problemas de salud.

Valores:

• Ética
• Compromiso
• Respeto
• Responsabilidad
• Lealtad

Líneas de Investigación:

• Enfermedades gastrointestinales
• Hepatopatías crónicas
• Nutrición y enfermedades metabólicas
• Inmunología en enfermedades hepáticas
• Nutrición y calidad de vida en hepatopatías

Miembros del grupo:

Publicaciones Recientes

• Andrea Del Carmen Maldonado-Rojas, Julia María Zuarth-Vázquez, Misael Uribe, Varenka J Barbero-Becerra. Insulin resistance and Metabolic dysfunction-associated steatotic liver disease (MASLD): Pathways of action of hypoglycemic agents. Ann Hepatol. 2023 Dec 1;29(2):101182. doi: 10.1016/j.aohep.2023.101182.
  https://pubmed.ncbi.nlm.nih.gov/38042482/
• Alejandra Mijangos-Trejo, Natalia Nuño-Lambarri, Varenka Barbero-Becerra, Misael Uribe-Esquivel, Paulina Vidal-Cevallos, Norberto Chávez-Tapia. Prebiotics and Probiotics: Therapeutic Tools for Nonalcoholic Fatty Liver Disease. Int J Mol Sci. 2023 Oct 5;24(19):14918. doi: 10.3390/ijms241914918
  https://pubmed.ncbi.nlm.nih.gov/37834367/
• Vidal-Cevallos P, Murúa-Beltrán Gall S, Uribe M, Chávez-Tapia NC. Understanding the Relationship between Nonalcoholic Fatty Liver Disease and Thyroid Disease. Int J Mol Sci. 2023 Sep 27;24(19):14605. doi: 10.3390/ijms241914605.
  https://pubmed.ncbi.nlm.nih.gov/37834051/
• Morales-Olvera CG, Lanz-Zubiría L, Aguilar-Zamora E, Camorlinga-Ponce M, Aparicio-Ozores G, Aguilar-Zapata D, Chávez-Tapia NC, Uribe M, Barbero-Becerra VJ, Juárez-Hernández E. Clostridioides Difficile in Latin America: An Epidemiological Overview. Curr Microbiol. 2023 Sep 28;80(11):357. doi: 10.1007/s00284-023-03475-x
  https://pubmed.ncbi.nlm.nih.gov/37768473/
• Iván López-Méndez, Andrea Del Carmen Maldonado-Rojas, Misael Uribe, Eva Juárez-Hernández. Hunger & satiety signals: another key mechanism involved in the NAFLD pathway. Front Endocrinol (Lausanne). 2023 Sep 11:14:1213372. doi: 10.3389/fendo.2023.1213372. eCollection 2023.
  https://pubmed.ncbi.nlm.nih.gov/37753211/
• Vidal-Cevallos P, Mijangos-Trejo A, Uribe M, Chávez-Tapia NC. The interlink between Metabolic-Associated Fatty Liver Disease and polycistic ovary syndrome. Endocrinol Metab Clin North Am. 2023 September;Vol.52(3):533-545
  https://www.endo.theclinics.com/article/S0889-8529(23)00005-1/fulltext
• Jorge Aquino-Matus, Eva Juárez-Hernández, Iván López-Méndez. Rendezvous technique and self-expandable metal stent for afferent limb syndrome. Endoscopia 2023;34(4):123-125
  doi.org/10.24875/END.23000013
  https://www.endoscopia-ameg.com/frame_eng.php?id=205
• Juan L. Romero-Flores, Eva Juárez-Hernández, Iván López-Mendez. Successful re-intervention with antegrade insertion of the metal stent into the hepaticojejunostomy through the hepaticogastrostomy route. Endoscopia.2023;34(4):126-128 doi.org/10.24875/END.23000014
  https://www.endoscopia-ameg.com/frame_eng.php?id=206
• Cárdenas-Fernández D, Soberanis Pina P, Turcott JG, Chávez-Tapia N, Conde-Flores E, Cardona AF, Arrieta O. Management of diarrhea induced by EGFR-TKIs in advanced lung adenocarcinoma. Ther Adv Med Oncol. 2023 Aug 24;15:17588359231192396.
  doi: 10.1177/17588359231192396. eCollection.
  https://pubmed.ncbi.nlm.nih.gov/37655206/
• Mena-Ramírez R, Macari-Jorge A, Juárez-Hernández E, Uribe M, López-Méndez I. Accuracy of Narrow-Band Imaging International Colorectal Endoscopic Classification for Predicting the Histology of Colon Polyps by Experienced Endoscopists and Trainees. Turk J Gastroenterol. 2023 Aug;34(8):866-872. doi: 10.5152/tjg.2023.22854.
  https://pubmed.ncbi.nlm.nih.gov/37533278/
• Manuel Romero-Gómez, Eric Lawitz, R, Jie Liu, Raymond L H Lam, Keith D Kaufman, Samuel S Engel, MK-6024 P001 Study Group(Norberto Carlos Chavez-Tapia). A phase IIa active-comparator-controlled study to evaluate the efficacy and safety of efinopegdutide in patients with non-alcoholic fatty liver disease. J Hepatol. Epub 2023 Jun 22.
  https://pubmed.ncbi.nlm.nih.gov/37355043/
• Torre A, Cisneros-Garza LE, Castillo-Barradas M, Navarro-Alvarez N, Sandoval-Salas R, González-Huezo MS, Pérez-Hernández JL, Méndez-Guerrero O, Ruiz-Manríquez JA, Trejo-Estrada R, Chavez-Tapia NC, et al. Consensus document on acute-on-chronic liver failure (ACLF) established by the Mexican Association of Hepatology. Ann Hepatol. 2023 Jul 22;28(6):101140.
  doi: 10.1016/j.aohep.2023.101140.
  https://pubmed.ncbi.nlm.nih.gov/37482299/
• Higuera-de-la-Tijera F, Velarde-Ruiz Velasco JA, Raña-Garibay RH, Castro-Narro GE, Abdo-Francis JM, Moreno-Alcántar R, Pérez-Hernández JL, Torre A, Contreras-Omaña R, Cano-Contreras A, Castillo-Barradas M, Pérez-Escobar J, Aldana-Ledesma JM, Cerda-Reyes E, Fernández-Pérez NJ, Meza-Cardona J, Flores-García NC, Reyes-Bastidas M, Lira-Vera JE, García-Jiménez ES, Santana-Vargas D, Páez-Zayas VM, Chávez-Tapia NC, Márquez-Guillén E. Current vision on diagnosis and comprehensive care in hepatic encephalopathy.
  Rev Gastroenterol Mex (Engl Ed). 2023 Apr 29;S2255-534X(23)00036-1
  https://pubmed.ncbi.nlm.nih.gov/37127462/
• Julia Zuarth-Vázquez, Lidia Moreno-Castañeda, Juan Pablo Soriano-Márquez, Alain Velázquez-Alemán, Martha Helena Ramos-Ostos, Misael Uribe, Iván López-Méndez, Eva Juárez-Hernández. Low-Normal Thyroid Function Is Not Associated with Either Non-Alcoholic Fatty Liver Disease or with Metabolic Dysfunction-Associated Fatty Liver Disease.
  Life (Basel). 2023 Apr 19;13(4):1048
  https://pubmed.ncbi.nlm.nih.gov/37109577/
• Manzo-Francisco LA, Aquino-Matus J, Vidaña-Pérez D, Uribe M, Chavez-Tapia N. Systematic review and meta-analysis: Transient elastography compared to liver biopsy for staging of liver fibrosis in primary biliary colangitis.
  Ann Hepatol. 2023 Apr;23;28(4):101107
  https://pubmed.ncbi.nlm.nih.gov/37088420/
• Martínez-Bohorquez MC, Carnalla M, Chávez-Tapia N, Barrientos-Gutiérrez T. Hepatitis C mortality trends in Mexico from 2001 to 2017. Ann Hepatol. 2023 May-Jun;28(3):101083. doi: 10.1016/j.aohep.2023.101083.
  https://pubmed.ncbi.nlm.nih.gov/36871855/
• Montalvo-Javé EE, Nuño-Lámbarri N, López-Sánchez GN, Ayala-Moreno EA, Gutierrez-Reyes G, Beane J, Pawlik TM. Pancreatic Cancer: Genetic Conditions and Epigenetic Alterations, J Gastrointest Surg.
  2023 May;27(5):1001-1010. Epub 2023 Feb 7
  https://pubmed.ncbi.nlm.nih.gov/36749558/
• Chávez-Tapia N. Change of courier for Annals of Hepatology. Ann Hepatol.
  2023 Jan-Feb;28(1):100893
  https://pubmed.ncbi.nlm.nih.gov/36608959/
• Rivera-Aguirre J, López-Sánchez GN, Carlos Chávez-Tapia N, Uribe M, Nuño-Lámbarri N. Metabolic-associated Fatty Liver Disease regulation through Nutri Epigenetic Methylation. Mini Rev Med Chem.
  2023 Jan 30
  https://pubmed.ncbi.nlm.nih.gov/36718062/
• Juárez-Hernández E, Velázquez-Alemán AP, Castro-Narro G, Uribe M, López-Méndez I. Bariatric endoscopic-surgical therapies for NAFLD. Should they be considered viable options among current treatments? Front Endocrinol (Lausanne). 2022 Nov 29;13:1026444.
  doi: 10.3389/fendo.2022.1026444. eCollection 2022
  https://pubmed.ncbi.nlm.nih.gov/36523596/
• Ordoñez-Vázquez AL, Juárez-Hernández E, Zuarth-Vázquez JM, Ramos-Ostos MH, Uribe M, Castro-Narro G, López-Méndez I. Impact on Prevalence of the Application of NAFLD/MAFLD Criteria in Overweight and Normal Weight Patients. Int J Environ Res Public Health. 2022 Sep 27;19(19):12221.
  doi: 10.3390/ijerph191912221
  https://pubmed.ncbi.nlm.nih.gov/36231529/
• Vidal-Cevallos P, Chávez-Tapia NC, Uribe M. Current approaches to hepatic encephalopathy. Ann Hepatol. 2022 Nov-Dec;27(6):100757.
  doi: 10.1016/j.aohep.2022.100757
  https://pubmed.ncbi.nlm.nih.gov/36115576/
• López-Sánchez GN, Montalvo-Javé E, Domínguez-Perez M, Antuna-Puente B, Beltrán-Anaya FO, Hidalgo-Miranda A, Chávez-Tapia NC, Uribe M, Nuño-Lámbarri N. Hepatic mir-122-3p, mir-140-5p and mir-148b-5p expressions are correlated with cytokeratin-18 serum levels in MAFLD. Ann Hepatol. 2022 Nov-Dec;27(6):100756.
  doi: 10.1016/j.aohep.2022.100756
  https://pubmed.ncbi.nlm.nih.gov/36096296/
• Aquino-Matus J, Uribe M, Chavez-Tapia N. COVID-19: Current Status in Gastrointestinal, Hepatic, and Pancreatic Diseases-A Concise Review. Trop Med Infect Dis. 2022 Aug 16;7(8):187.
  doi: 10.3390/tropicalmed7080187
  https://pubmed.ncbi.nlm.nih.gov/36006279/
• Chavez-Tapia NC, Murúa-Beltrán Gall S, Ordoñez-Vázquez AL, Nuño-Lambarri N, Vidal-Cevallos P, Uribe M. Understanding the Role of Metabolic Syndrome as a Risk Factor for Hepatocellular Carcinoma. J Hepatocell Carcinoma. 2022 Jul 5;9:583-593.
  doi: 10.2147/JHC.S283840
  https://pubmed.ncbi.nlm.nih.gov/35818404/
• Montgomery H, Hobbs FDR, Padilla F, Arbetter D, Templeton A, Seegobin S, Kim K, Campos JAS, Arends RH, Brodek BH, Brooks D, Garbes P, Jimenez J, Koh GCKW, Padilla KW, Streicher K, Viani RM, Alagappan V, Pangalos MN, Esser MT, Abe W, Adan De Varona T, Adiatullina D, Aguilar Zapata D, Ahlers K, Aimo C, Akere A, Akimova E, Alatorre-Alexander J, Aldrich L, Ali- Garcia I, Ali-García K, Allison L, Alonso-Zuñiga R, Aloysius I, Altclas J, Alvarisqueta A, Antila M, Anton C, Árboix-Alamo E, Arora S, Ramón Alejandro Avilés-Felix RA, Bakhtina N, Barbero-Becerra V, et al. Efficacy and safety of intramuscular administration of tixagevimab-cilgavimab for early outpatient treatment of COVID-19 (TACKLE): a phase 3, randomised, double-blind, placebo-controlled trial. Lancet Respir Med. 2022 Oct;10(10):985-996.
  doi: 10.1016/S2213-2600(22)00180-1
  https://pubmed.ncbi.nlm.nih.gov/35688164/
• Chavez-Tapia NC, Barrientos-Gutierrez T, Torres-Ibarra L, Sanchez-Jiménez B, Juarez-Hernandez E, Ramos-Ostos M, Alva-Lopez LF, Uribe M. Incremental levels of diagnostic information incentivize health-seeking in non-alcoholic fatty liver: a randomized clinical trial. Sci Rep 2022 May 18;12(1):8272.
  doi: 10.1038/s41598-022-12295-1
  https://pubmed.ncbi.nlm.nih.gov/35585153/
• Díaz LA, Fuentes-López E, Ayares G, Idalsoaga F, Arnold J, Márquez-Lomas A, Ramírez CA, Medel MP, Viñuela F, Lacalle L, Roblero JP, Ferreccio C, Lazo M, Brahmania M, Singal AK, Dirchwolf M, Méndez-Sánchez N, Chavez-Tapia N, Guerra P, Restrepo JC, Oliveira CP, Lombardo J, Sánchez A, Elizondo M, Tagle M, Padilla M, Sánchez M, Carrera E, Girala M, Chery O, Castellanos-Fernández M, Barrera F, Lazarus JV, Kamath PS, Bataller R, Arrese M, Arab JP. The establishment of public health policies and the burden of non-alcoholic fatty liver disease in the Americas. Lancet Gastroenterol Hepatol. 2022 Jun;7(6):552-559.
  doi: 10.1016/S2468-1253(22)00008-5
  https://pubmed.ncbi.nlm.nih.gov/35430032/
• Aguilar-Zamora E, Weimer BC, Torres RC, Gómez-Delgado A, Ortiz-Olvera N, Aparicio-Ozores G, Barbero-Becerra VJ, Torres J, Camorlinga-Ponce M. Molecular Epidemiology and Antimicrobial Resistance of Clostridioides difficile in Hospitalized Patients From Mexico. Front Microbiol. 2022 Mar 10;12:787451.
  doi: 10.3389/fmicb.2021.787451
  https://pubmed.ncbi.nlm.nih.gov/35360652/
• Vidal-Cevallos P, Torre A, Mendez-Sanchez N, Uribe M, Chavez-Tapia NC. Epidemiological and Genetic Aspects of NAFLD and NASH in Mexico. Clin Liver Dis (Hoboken). 2022 Mar 10;19(2):68-72.
  doi: 10.1002/cld.1167. eCollection 2022 Feb
  https://pubmed.ncbi.nlm.nih.gov/35308477/
• Méndez-Sánchez N, Bugianesi E, Gish RG, Lammert F, Tilg H, Nguyen MH, Sarin SK, Fabrellas N, Zelber-Sagi S, Fan JG, Shiha G, Targher G, Zheng MH, Chan WK, Vinker S, Kawaguchi T, Castera L, Yilmaz Y, Korenjak M, Spearman CW, Ungan M, Palmer M, El-Shabrawi M, Gruss HJ, Dufour JF, Dhawan A, Wedemeyer H, George J, Valenti L, Fouad Y, Romero-Gomez M, Eslam M; Chávez-Tapia NC Global multi-stakeholder endorsement of the MAFLD definition. Lancet Gastroenterol Hepatol. 2022 May;7(5):388-390.
  doi: 10.1016/S2468-1253(22)00062-0
  https://pubmed.ncbi.nlm.nih.gov/35248211/
• Pérez-Monter C, Álvarez-Arce A, Nuño-Lambarri N, Escalona-Nández I, Juárez-Hernández E, Chávez-Tapia NC, Uribe M, Barbero-Becerra VJ. Inulin Improves Diet-Induced Hepatic Steatosis and Increases Intestinal Akkermansia Genus Level. Int J Mol Sci. 2022 Jan 17;23(2):991.
  doi: 10.3390/ijms23020991
  https://pubmed.ncbi.nlm.nih.gov/35055177/
• Rodríguez-Antonio I, López-Sánchez GN, Reyes-Gómez VA, Contreras-Flores EH, Farías-García F, Espejel-Deloiza M, Durán-Padilla MA, Chablé-Montero F, Uribe M, Chávez-Tapia NC, Montalvo-Javé EE, Nuño-Lámbarri N. Laparoscopic cholecystectomy: Histopathological analysis of metabolic associated fatty liver disease and fibrosis. Ann Hepatol. 2022 Mar-Apr;27(2):100651.
  doi: 10.1016/j.aohep.2021.100651. Epub 2021 Dec 9
  https://pubmed.ncbi.nlm.nih.gov/34896638/
• Carnalla M, Vidaña-Pérez D, Alpuche-Aranda C, Chávez-Tapia NC, Romero-Martínez M, Shamah-Levy T, Barrientos-Gutiérrez T. Hepatitis B infection in Mexican adults: Results of a nationally representative survey. Ann Hepatol. 2022 Jan;27 Suppl 1:100583. Epub 2021 Nov 19.
  doi: 10.1016/j.aohep.2021.100583.
  https://pubmed.ncbi.nlm.nih.gov/34808394
• Chávez-Tapia NC, Tiribelli C. The multifaceted aspects of modern hepatology. Ann Hepatol. 2021 Dec;26:100536.
  doi: 10.1016/j.aohep.2021.100536.
  https://pubmed.ncbi.nlm.nih.gov/34547479
• Vidal-Cevallos P, Ordóñez-Vázquez AL, Procopio-Mosso O, Cardoso-Arias R, Uribe Chávez-Tapia NC. Cross-sectional pilot study to assess primary healthcare workers' knowledge of nonalcoholic fatty liver disease in a marginalized community in Mexico. M, Sci Rep. 2021 Jun 8;11(1):12100.
  doi: 10.1038/s41598-021-91199-y.
  https://pubmed.ncbi.nlm.nih.gov/34103552
• Rodríguez-Antonio I, López-Sánchez GN, Uribe M, Chávez-Tapia NC, Nuño-Lámbarri N. Role of the inflammasome, gasdermin D, and pyroptosis in non-alcoholic fatty liver disease. Gastroenterol Hepatol. 2021 May 28.
  doi: 10.1111/jgh.15561.
  https://pubmed.ncbi.nlm.nih.gov/34050551
• Vidal-Cevallos P, Chávez-Tapia N. Very-early-stage Hepatocellular Carcinoma, Are We at Long Last on Route for Achieving Better Patient Outcomes? J Clin Transl Hepatol. 2021 Apr 28;9(2):141-142.
  doi: 10.14218/JCTH.2021.00137
  https://pubmed.ncbi.nlm.nih.gov/34007794
• Vidal-Cevallos P, Higuera-De-La-Tijera F, Chávez-Tapia NC, Sánchez-Girón F, Reyes EC, Rosales-Salyano VH, Servin-Caamaño A, Vázquez-Medina MU, Méndez-Sánchez N. Reply to: Lactate-dehydrogenase associated with mortality in hospitalized patients with COVID-19 in Mexico. Ann Hepatol. 2021 Apr 24;24:100354.
  doi: 10.1016/j.aohep.2021.100354.
  https://pubmed.ncbi.nlm.nih.gov/33901638
• Mendizabal M, Ridruejo E, Piñero F, Anders M, Padilla M, Toro LG, Torre A, Montes P, Urzúa A, Ballerga EG, Silveyra MD, Michelato D, Díaz J, Peralta M, Pages J, García SR, Lozano IG, Macias Y, Cocozzella D, Chávez-Tapia N, Tagle M, Dominguez A, Varón A, Pozo EV, Tijera FH, Bustios C, Conte D, Escajadillo N, Gómez AJ, Tenorio L, Barradas MC, Schinoni MI, Bessone F, Contreras F, Nazal L, Sanchez A, García M, Brutti J, Cabrera MC, Miranda-Zazueta G, Rojas G, Cattaneo M, Castro-Narro G, Rubinstein F, Silva MO. Comparison of different prognostic scores for patients with cirrhosis hospitalized with SARS-CoV-2 infection. Ann Hepatol. 2021 Apr 14;100350.
  doi: 10.1016/j.aohep.2021.100350
  https://pubmed.ncbi.nlm.nih.gov/33864948
• Vidal-Cevallos P, Higuera-De-La-Tijera F, Chávez-Tapia NC, Sanchez-Giron F, Cerda-Reyes E, Rosales-Salyano VH, Servin-Caamaño A, Vázquez-Medina MU, Méndez-Sánchez N. Lactate-dehydrogenase associated with mortality in hospitalized patients with COVID-19 in Mexico: a multi-centre retrospective cohort study. Ann Hepatol. 2021 Feb 26;24:100338.
  doi: 10.1016/j.aohep.2021.100338
  https://pubmed.ncbi.nlm.nih.gov/33647501
• López-Méndez Iván, Méndez-Maldonado Karla, Manzo-Francisco Luis A, Juárez-Hernández Eva, Uribe Misael, Barbero-Becerra Varenka J. G protein-coupled receptors: Key molecules in metabolic associated fatty liver disease development. Nutr Res. 2021 Mar;87:70-79. doi: 10.1016/j.nutres.2020.12.019. Epub 2020 Dec 24.
  https://pubmed.ncbi.nlm.nih.gov/33601216/
• Romano-Munive AF, García-Correa JJ, García-Contreras LF, Ramírez-García J, Uscanga L, Barbero-Becerra VJ, Moctezuma-Velázquez C, Ochoa-Rubí JA, Toledo-Cuque J, Vázquez-Anaya G, Keil-Ríos D, Grajales-Figueroa G, Ramírez-Luna MÁ, Valdovinos-Andraca F, Zamora-Nava LE, Tellez-Avila F. Can topical epinephrine application to the papilla prevent pancreatitis after endoscopic retrograde cholangiopancreatography? Results from a double blind, multicentre, placebo controlled, randomised clinical trial. BMJ Open Gastroenterol. 2021 Feb;8(1):e000562.
  doi:10.1136/bmjgast-2020-000562.
  https://pubmed.ncbi.nlm.nih.gov/33558263
• Botello-Manilla AE, López-Sánchez GN, Chávez-Tapia NC, Uribe M, Nuño-Lámbarri N. Hepatic steatosis and respiratory diseases: a new panorama. Ann Hepatol. 2021 Sep-Oct;24:100320. Epub 2021 Feb 4.
  doi: 10.1016/j.aohep.2021.
  https://pubmed.ncbi.nlm.nih.gov/33549735
• Valdivia-Correa B, Reynier-Garza V, Chávez-Tapia N, Alanis-Estrada G, Araiza-Garaygordobil D. Acute heart failure following transjugular intrahepatic portal-systemic shunting corrected through transient balloon occlusion. Rev Gastroenterol Mex. Apr-Jun 2021;86(2):195-197.
  doi: 10.1016/j.rgmx.2020.04.009. Epub 2021 Jan 30.
  https://pubmed.ncbi.nlm.nih.gov/33531166
• Botello-Manilla AE, López-Sánchez GN, Chávez-Tapia NC, Uribe M, Nuño-Lámbarri N. Hepatic steatosis and respiratory diseases: a new panorama. Ann Hepatol. 2021 Feb 4;24:100320. doi: 10.1016/j.aohep.2021.100320.
  https://pubmed.ncbi.nlm.nih.gov/33549735
• Valdivia-Correa B, Reynier-Garza V, Chávez-Tapia N, Alanis-Estrada G, Araiza-Garaygordobil D. Acute heart failure following transjugular intrahepatic portal-systemic shunting corrected through transient balloon occlusion. Rev Gastroenterol Mex. Apr-Jun 2021;86(2):195-197.
  doi: 10.1016/j.rgmx.2020.04.009. Epub 2021 Jan 30.
  https://pubmed.ncbi.nlm.nih.gov/33531166
• Calderón-Esquivel Néstor, Vázquez-Flores A David, González-Chon Octavio, García-Briones Alondra, Gutiérrez-Villaseñor Alan O, Romero-González Juan P, Juárez-Hernández Eva, Sosa-García J Ojino. [Correlación de variables ecocardiográficas y biomarcadores en pacientes graves con COVID-19]. Cir Cir. 2020 Dec 9.
  doi: 10.24875/CIRU.20000900.
  https://pubmed.ncbi.nlm.nih.gov/33296911/
• Mendez-Sanchez N, Arrese M, Gadano A, Oliveira CP, Fassio E, Arab JP, Chávez-Tapia NC, Dirchwolf M, Torre A, Ridruejo E, Pinchemel-Cotrim H, Castellanos Fernández MI, Uribe M, Girala M, Diaz-Ferrer J, Restrepo JC, Padilla-Machaca M, Dagher L, Gatica M, Olaechea B, Pessôa MG, Silva M. The Latin American Association for the Study of the Liver (ALEH) position statement on the redefinition of fatty liver disease. Lancet Gastroenterol Hepatol. 2021 Jan;6(1):65-72.
  doi: 10.1016/S2468-1253(20)30340-X
  https://pubmed.ncbi.nlm.nih.gov/33181118
• López-Méndez Iván, Aquino-Matus Jorge, Murua-Beltrán Gall Sofia, Prieto-Nava José D, Juárez-Hernández Eva, Uribe Misael, Castro-Narro Graciela. Ann Hepatol. Association of liver steatosis and fibrosis with clinical outcomes in patients with SARS-CoV-2 infection (COVID-19)
  2021 Jan-Feb;20:100271. doi: 10.1016/j.aohep.2020.09.015
  https://pubmed.ncbi.nlm.nih.gov/33099028/
• Sosa-García J Ojino, Gutiérrez-Villaseñor Alan O, García-Briones Alondra, Romero-González Juan P, Juárez-Hernández Eva, González-Chon Octavio. Experience in the management of severe COVID-19 patients in an intensive care unit. Cir Cir. 2020;88(5):569-575.
  doi: 10.24875/CIRU.20000675
  https://pubmed.ncbi.nlm.nih.gov/33064694/
• Rodríguez-Antonio I, López-Sánchez GN, Garrido-Camacho VY, Uribe M, Chávez-Tapia NC, Nuño-Lámbarri N. Cholecystectomy as a risk factor for non-alcoholic fatty liver disease development. HPB (Oxford). 2020 Aug 6;S1365-182X(20)31105-9.
  doi: barbero10.1016/j.hpb.2020.07.011
  https://pubmed.ncbi.nlm.nih.gov/32773176
• López-Bautista F, Barbero-Becerra VJ, Ríos MY, Ramírez-Cisneros MÁ, Sánchez-Pérez CA, Ramos-Ostos MH, Uribe M, Chávez-Tapia NC, Juárez-Hernández E. Dietary consumption and serum pattern of bioactive fatty acids in NAFLD patients. Ann Hepatol. Sep-Oct 2020;19(5):482-488.
  doi: 10.1016/j.aohep.2020.06.008.
  https://pubmed.ncbi.nlm.nih.gov/32717363
• Vidal-González D, López-Sánchez GN, Concha-Rebollar LA, Rodríguez-Herrera A, Morales-Ramirez F, Chávez-Tapia N, Uribe M, Nader-Kawachi JA, Nuño-Lámbarri N. Cerebral hemodynamics in the non-alcoholic fatty liver. Ann Hepatol. 2020 Jul 16:S1665-2681(20)30067-3.
  doi: 10.1016/j.aohep.2020.06.006.
  https://pubmed.ncbi.nlm.nih.gov/32683094
• Botello-Manilla AE, Chávez-Tapia NC, Uribe M, Nuño-Lámbarri N. Genetics and epigenetics purpose in nonalcoholic fatty liver disease. Expert Rev Gastroenterol Hepatol. 2020 Aug;14(8):733-748.
  doi:10.1080/17474124.2020.1780915.
  https://pubmed.ncbi.nlm.nih.gov/32552211
• Martínez-Zavala N, López-Sánchez GN, Vergara-Lopez A, Chávez-Tapia NC, Uribe M, Nuño-Lámbarri N. Vitamin D deficiency in Mexicans have a high prevalence: a cross-sectional analysis of the patients from the Centro Médico Nacional 20 de Noviembre. Arch Osteoporos. 2020 Jun 16;15(1):88.
  doi: 10.1007/s11657-020-00765-w.
  https://pubmed.ncbi.nlm.nih.gov/32542548
• López-Sánchez GN, Dóminguez-Pérez M, Uribe M, Chávez-Tapia NC, Nuño-Lámbarri N. Non-alcoholic fatty liver disease and microRNAs expression, how it affects the development and progression of the disease. Ann Hepatol. 2020 Jun 6;S1665-2681.
  doi: 10.1016/j.aohep.2020.04.012
  https://pubmed.ncbi.nlm.nih.gov/32533953
• Valencia-Rodríguez A, Vera-Barajas A, Chávez-Tapia NC, Uribe M, Méndez-Sánchez N. Looking Into a New Era for the Approach of Metabolic (Dysfunction) Associated Fatty Liver Disease. Ann Hepatol.2020;19(3):227-229.
  doi: 10.1016/j.aohep.2020.04.001.
  https://pubmed.ncbi.nlm.nih.gov/32359519
• Barbero-Becerra VJ, López-Méndez I, Romo-Araiza A, Visag-Castillo V, Chávez-Tapia NC, Uribe M, Juárez-Hernández E. Sarcopenia in Chronic Liver Diseases: A Translational Overview. Expert Rev Gastroenterol Hepatol. 2020;14(5):355-366.
  doi: 10.1080/17474124.2020.1757427.
  https://pubmed.ncbi.nlm.nih.gov/32299261
• Salva-Pastor N, López-Sánchez GN, Chávez-Tapia NC, Audifred-Salomón JR, Niebla-Cárdenas D, Topete-Estrada R, Pereznuñez-Zamora H, Vidaltamayo-Ramírez R, Báez-Arellano ME, Uribe M, Nuño-Lámbarri N. Polycystic Ovary Syndrome With Feasible Equivalence to Overweight as a Risk Factor for Non-Alcoholic Fatty Liver Disease Development and Severity in Mexican Population. Ann Hepatol.2020;5:S1665-2681.
  doi: 10.1016 / j.aohep.2020.01.004
  https://pubmed.ncbi.nlm.nih.gov/32111488
• Salva-Pastor N, Chávez-Tapia NC, Uribe M, Nuño-Lámbarri N. The diagnostic and initial approach of the patient with non-alcoholic fatty liver disease: role of the primary care provider. Gastroenterol Hepatol Bed Bench. 2019 Fall;12(4):267-277.
  PMCID: PMC6820831
  https://www.ncbi.nlm.nih.gov/pubmed/31749914
• Juárez-Hernández E, Uribe M. The lack of guidelines and government policies for regulating nonprescription sale of antibiotics and its medical consequences.1 Ann Hepatol. 2019;18(6):783-785.
  doi: 10.1016/j.aohep.2019.10.001
  https://www.ncbi.nlm.nih.gov/pubmed/31735347
• Chávez-Tapia N. The bidirectional relationship between viral hepatitis infections and work. Ann Hepatol. 2019;18(5):655.
  doi: 10.1016 / j.aohep.2019.07.001
  https://www.ncbi.nlm.nih.gov/pubmed/31416707
• Salva-Pastor N, Chávez-Tapia NC, Uribe M, Nuño-Lámbarri N. Understanding the association of polycystic ovary syndrome and non-alcoholic fatty liver disease. J Steroid Biochem Mol Biol. 2019;2;194:105445.
  doi: 10.1016/j.jsbmb.2019.105445
  https://www.ncbi.nlm.nih.gov/pubmed/31381969
• López-Sánchez GN, Dóminguez-Pérez M, Uribe M, Nuño-Lámbarri N. The fibrogenic process and the unleashing of acute-on-chronic liver failure. Clinical and Molecular Hepatology. 2019:14.
  doi: 10.3350/cmh.2019.0011.
  https://www.ncbi.nlm.nih.gov/pubmed/31195778
• Solsona-Vilarrasa E, Fucho R, Torres S, Nuñez S, Nuño-Lámbarri N, Enrich C, García-Ruiz C, Fernández-Checa JC. Cholesterol enrichment in liver mitochondria impairs oxidative phosphorylation and disrupts the assembly of respiratory supercomplexes.Redox Biology. 2019;24:101214.
  doi: 10.1016/j.redox.2019.101214.
  https://www.ncbi.nlm.nih.gov/pubmed/31108462
• Bernal-Reyes R, Castro-Narro G, Malé-Velázquez R, Carmona-Sánchez R, González-Huezo MS, García-Juárez I, Chávez-Tapia N, et al. The Mexican consensus on nonalcoholic fatty liver disease. Revista de Gastroenterología de México 2019;84(1):69-99.
  doi: 10.1016/j.rgmx.2018.11.007.
  https://www.ncbi.nlm.nih.gov/pubmed/30711302
• Domínguez-Pérez M, Simoni-Nieves A, Rosales P, Nuño-Lámbarri N, Rosas-Lemus M, Souza V, et al. Cholesterol burden in the liver induces mitochondrial dynamic changes and resistance to apoptosis. Journal of Cellular Physiology. 2019;234(5):7213-7223.
  doi:10.1002/jcp.27474
  https://www.ncbi.nlm.nih.gov/pubmed/30239004
• Bazerbachi F, Haffar S, Wang Z, González JC, Arias-Loste MT, Crespo J, Darwish-Murad S, Ikram MA, Olynyk JK, Gan E, Petta S, Berzuini A, Prati D, de Lédinghen V, Wong VW, Del Poggio P, Chávez-Tapia NC, et al. Range of Normal Liver Stiffness and Factors Associated With Increased Stiffness Measurements in Apparently Healthy Individuals. Clin Gastroenterol Hepatol. 2019;17(1):54-64.e1.
  doi: 10.1016/j.cgh.2018.08.069.
  https://pubmed.ncbi.nlm.nih.gov/30196155

Responsable:

Dr. Norberto Chávez Tapia
Director de la Unidad de Investigación Traslacional
nchavezt@medicasur.org.mx

Información sujeta a cambio sin previo aviso 29/FEB/2024 STHC