Producción Científica

El Grupo Médica Sur tiene el honor de contar con varios investigadores que pertenecen al Sistema Nacional de Investigadores (SNI) del Consejo Nacional de Ciencia y Tecnología (CONACyT) y que reciben un estímulo económico por parte de la Fundación Clínica Médica Sur:

• Misael Uribe Esquivel, Nivel Emérito
• Norberto Carlos Chávez Tapia, Nivel II
• Désirée Erlinda Larenas Linneman, Nivel II
• María Adela Poitevin Chacón, Nivel II
• Nancy Edith Aguilar Olivos, Nivel I
• Varenka J. Barbero Becerra, Nivel I
• Rita Dorantes Heredia, Nivel I
• Eduardo González Pier, Nivel I
• Daniel Motola Kuba, Nivel I
• Natalia Nuño Lambarri, Nivel I
• José Manuel Ruiz Morales, Nivel I

Gracias a la labor de estos investigadores en el segundo trimestre de 2019 se logró la publicación de 4 artículos, 3 en revistas nacionales y 1 en revista internacional.

Publicaciones Recientes

• Pali-Schöll I, Meinlschmidt P, Larenas-Linnemann D, Purschke B, Hofstetter G, Rodríguez-Monroy FA, et.al. Edible insects: Cross-recognition of IgE from crustacean- and house dust mite allergic patients, and reduction of allergenicity by food processing. World Allergy Organization Journal. 2019 Jan 26;12(1):100006. doi: 10.1016/j.waojou.2018.10.001
  https://www.ncbi.nlm.nih.gov/pubmed/30937131
• Chavannes NH, Reitsma S, Cruz AA, da Silva J, Serpa FS, Larenas-Linnemann D, et.al. Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma. Clinical and Translational Allergy. 2019 Mar 11;9:16. doi: 10.1186/s13601-019-0252-0.
  https://www.ncbi.nlm.nih.gov/pubmed/30911372
• Panopoulou G, Gonzalez-Pier E. Challenges in HIV infection control in transgender women sex workers. The Lancet Public Health. 2019 Mar;4(3):e117-e118. doi: 10.1016/S2468-2667(18)30259-7.
  https://www.ncbi.nlm.nih.gov/pubmed/30683586
• Dávila-Dupont D, Motola-Kuba D, Dorantes-Heredia R, González-Alonso BK, Alcántara-Velarde T, García-Santisteban R, Martínez-Sámano JE, Grimaldo-Roque HJ, Ruiz-Morales JM. Risk of Pneumonitis with the Use of Different Immune Checkpoint Inhibitors in a Mexican Population. Oncology. 2019;96(5):268-272. doi: 10.1159/000497405.
  https://www.ncbi.nlm.nih.gov/pubmed/30861515
• Dorantes-Heredia R, Motola-Kuba D, Murphy-Sanchez C, Izquierdo-Tolosa CD, Ruiz-Morales JM. Spontaneous regression as a 'burned-out' non-seminomatous testicular germ cell tumor: a case report and literature review. Journal of Surgical Case Reports.  2019 Jan 9;2019(1):rjy358. doi: 10.1093/jscr/rjy358.
  https://www.ncbi.nlm.nih.gov/pubmed/30647899
• Bernal-Reyes R, Castro-Narro G, Malé-Velázquez R, Carmona-Sánchez R, González-Huezo MS, García-Juárez I, Chávez-Tapia N, et al. The Mexican consensus on nonalcoholic fatty liver disease. Revista de Gastroenterología de México 2019 Jan - Mar;84(1):69-99. doi: 10.1016/j.rgmx.2018.11.007.
  https://www.ncbi.nlm.nih.gov/pubmed/30711302
• Devillier P, De Vries G, Keil T, Sheikh A, Orlando V, Larenas-Linnemann D. et al. Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study. Clinical & Experimental Allergy. 2019 Apr;49(4):442-460.
  doi: 10.1111/cea.13333.
  https://www.ncbi.nlm.nih.gov/pubmed/30597673
• Larenas-Linnemann D, Mullol J, Ivancevich JC, Anto JM, Cardona V, Dedeu T, et al. MASK (Mobile Airways Sentinel Network), a mobile App with ARIA's comprehensive solution in Spanish-speaking countries. Revista Alergia México. 2019;66(2):263-268. doi:10.29262/ram.v66i2.628
  https://www.ncbi.nlm.nih.gov/pubmed/31200425
• Larenas-Linnemann D, Luna-Pech JA, Rodríguez-Pérez N, Rodríguez-González M, Arias-Cruz A, Blandón-Vijil MV, et al. GUIMIT 2019, Mexican Guideline on Immunotherapy. Guideline on the diagnosis of IgE-mediated allergic disease and immunotherapy following the ADAPTE approach.  Revista Alergia México. 66 Suppl 1:1-105. doi: 10.29262/ram.v66i5.631.
  https://www.ncbi.nlm.nih.gov/pubmed/31200597
• López-Sánchez GN, Dóminguez-Pérez M, Uribe M, Nuño-Lámbarri N. The fibrogenic process and the unleashing of acute-on-chronic liver failure. Clinical and Molecular Hepatology. 2019:14. doi: 10.3350/cmh.2019.0011.
  https://www.ncbi.nlm.nih.gov/pubmed/31195778
• Solsona-Vilarrasa E, Fucho R, Torres S, Nuñez S, Nuño-Lámbarri N, Enrich C, García-Ruiz C, Fernández-Checa JC. Cholesterol enrichment in liver mitochondria impairs oxidative phosphorylation and disrupts the assembly of respiratory supercomplexes.Redox Biology. 2019 Jun;24:101214.  doi: 10.1016/j.redox.2019.101214.   
  https://www.ncbi.nlm.nih.gov/pubmed/31108462
• Domínguez-Pérez M, Simoni-Nieves A, Rosales P, Nuño-Lámbarri N, Rosas-Lemus M, Souza V, et al. Cholesterol burden in the liver induces mitochondrial dynamic changes and resistance to apoptosis. Journal of Cellular Physiology. 2019;234(5):7213-7223. Doi:10.1002/jcp.27474
  https://www.ncbi.nlm.nih.gov/pubmed/30239004
• Czarlewski W, Murray R, Almeida R, Fonseca J, Costa E, Malva J, Morais-Almeida M, Pereira AM, Todo-Bom A, Menditto E, Stellato C, Ventura MT, Cruz AA, Stelmach R, da Silva J, Larenas-Linnemann D, et al. Mobile technology offers novel insights into the control and treatment of allergic rhinitis: The MASK study. Journal of Allergy and Clinical Immunology. 2019;144(1):135-143.
  https://www.ncbi.nlm.nih.gov/pubmed/30951790
• Bousquet J, Ansotegui IJ, Anto JM, Arnavielhe S, Bachert C, Basagaña X, Bédard A, Bedbrook A, Bonini M, Bosnic-Anticevich S, Braido F, Cardona V, Czarlewski W, Cruz AA, Demoly P, De Vries G, Dramburg S, Mathieu-Dupas E, Erhola M, Fokkens WJ, Fonseca JA, Haahtela T, Hellings PW, Illario M, Ivancevich JC, Jormanainen V, Klimek L, Kuna P, Kvedariene V, Laune D, Larenas-Linnemann D, et al. Mobile Technology in Allergic Rhinitis: Evolution in Management or Revolution in Health and Care? Journal of Allergy and Clinical Immunology: In Practice. 2019: S2213-2198(19)30721-4.
  https://www.ncbi.nlm.nih.gov/pubmed/31445223
• Domínguez-Pérez M, Simoni-Nieves A, Rosales P,  Nuño-Lámbarri N, Rosas-Lemus M, Souza V,  et al. Cholesterol burden in the liver induces mitochondrial dynamic changes and resistance to apoptosis. Journal of Cellular Physiology. 2019;234(5):7213-7223. Doi:10.1002/jcp.27474
  www.ncbi.nlm.nih.gov/pubmed/30239004
• ...Dykewicz MS, Gaga M, El-Gamal Y, Fonseca J, Fokkens WJ, Guzmán MA, Haahtela T, Hellings PW, Illario M, Ivancevich JC, Just J, Kaidashev I, Khaitov M, Khaltaev N, Keil T, Klimek L, Kowalski ML, Kuna P, Kvedariene V, Larenas-Linnemann D, et al. ARIA pharmacy 2018 "Allergic rhinitis care pathways for community pharmacy": AIRWAYS ICPs initiative (European Innovation Partnership on Active and Healthy Ageing, DG CONNECT and DG Santé) POLLAR (Impact of Air POLLution on Asthma and Rhinitis) GARD Demonstration project. Allergy. 2019 Jul;74(7):1219-1236. doi: 10.1111/all.13701. www.ncbi.nlm.nih.gov/pubmed/30565275
• Devillier P, De Vries G, Keil T, Sheikh A, Orlando V, Larenas-Linnemann D. et al. Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study. Clinical & Experimental Allergy. 2019;Apr49(4):442-460.
  doi: 10.1111/cea.13333.

  www.ncbi.nlm.nih.gov/pubmed/30597673

• Dorantes-Heredia R, Motola-Kuba D, Murphy-Sanchez C, Izquierdo-Tolosa CD, Ruiz-Morales JM. Spontaneous regression as a 'burned-out' non-seminomatous testicular germ cell tumor: a case report and literature review. Journal of Surgical Case Reports. 2019;Jan9;2019(1):rjy358. doi: 10.1093/jscr/rjy358.
  www.ncbi.nlm.nih.gov/pubmed/30647899
• Panopoulou G, Gonzalez-Pier E. Challenges in HIV infection control in transgender women sex workers. The Lancet Public Health. 2019 Mar;4(3):e117-e118. doi: 10.1016/S2468-2667(18)30259-7.
  www.ncbi.nlm.nih.gov/pubmed/30683586
• Bernal-Reyes R, Castro-Narro G, Malé-Velázquez R, Carmona-Sánchez R, González-Huezo MS, García-Juárez I,  Chávez-Tapia N, et al. The Mexican consensus on nonalcoholic fatty liver disease. Revista de Gastroenterología de México 2019 Jan - Mar;84(1):69-99. doi: 10.1016/j.rgmx.2018.11.007.
  www.ncbi.nlm.nih.gov/pubmed/30711302
• Dávila-Dupont D, Motola-Kuba D, Dorantes-Heredia R, González-Alonso BK, Alcántara-Velarde T, García-Santisteban R, Martínez-Sámano JE, Grimaldo-Roque HJ, Ruiz-Morales JM. Risk of Pneumonitis with the Use of Different Immune Checkpoint Inhibitors in a Mexican Population. Oncology. 2019;96(5):268-272. doi: 10.1159/000497405.
  www.ncbi.nlm.nih.gov/pubmed/30861515
• Chavannes NH, Reitsma S, Cruz AA, da Silva J, Serpa FS, Larenas-Linnemann D, et.al. Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma. Clinical and Translational Allergy. 2019 Mar 11;9:16. doi: 10.1186/s13601-019-0252-0.
  www.ncbi.nlm.nih.gov/pubmed/30911372
• Pali-Schöll I, Meinlschmidt P, Larenas-Linnemann D, Purschke B, Hofstetter G, Rodríguez-Monroy FA, et.al. Edible insects: Cross-recognition of IgE from crustacean- and house dust mite allergic patients, and reduction of allergenicity by food processing. World Allergy Organization Journal. 2019 Jan 26;12(1):100006.

  doi: 10.1016/j.waojou.2018.10.001
  www.ncbi.nlm.nih.gov/pubmed/30937131

• Czarlewski W, Murray R, Almeida R, Fonseca J, Costa E, Malva J, Morais-Almeida M, Pereira AM, Todo-Bom A, Menditto E, Stellato C, Ventura MT, Cruz AA, Stelmach R, da Silva J,  Larenas-Linnemann D, et al. Mobile technology offers novel insights into the control and treatment of allergic rhinitis: The MASK study. Journal of Allergy and Clinical Immunology. 2019;144(1):135-143.
  www.ncbi.nlm.nih.gov/pubmed/30951790
• Hellings PW, Lerodiakonou D, Linuma T, Ivancevich JC, Jacobsen L, Jutel M, Kaidashev I, Khaitov M, Kalayci O, Kleine Tebbe J, Klimek L, Kowalski ML, Kuna P, Kvedariene V, La Grutta, Larenas-Linemann D, et al. 2019 ARIA Care pathways for allergen immunotherapy. Allergy. 2019 Nov;74(11):2087-2102. doi: 10.1111/all.13805. www.ncbi.nlm.nih.gov/pubmed/30955224
• Larenas-Linnemann D, Mullol J, Ivancevich JC, Antó JM, Cardona V, Dedeu T, Rodríguez-González M, Huerta Y, Neffen H, Fuentes-Pérez JM, et al. MASK (Mobile Airways Sentinel Network). ARIA's comprehensive solution for mobile app for the multimorbidity of allergic rhinitis and asthma. Rev Alerg Mex. 2019;66 (1):140-146. doi: 10.29262/ram.v66i1.578. www.ncbi.nlm.nih.gov/pubmed/31013416
• Conde-Flores E, Dorantes-Heredia R, Motola-Kuba D, Grimaldo-Roque HJ, Martínez-Sámano JE, Ruiz-Morales JM. Epidemiological Profile of Patients of Aged 65 Years and Over in a University Private Hospital. Case Rep Oncol. 2019 Jan 24;12(1):113-118. doi: 10.1159/000496812. www.ncbi.nlm.nih.gov/pubmed/31043948
• Solsona-Vilarrasa E, Fucho R, Torres S, Nuñez S,  Nuño-Lámbarri N, Enrich C, García-Ruiz C, Fernández-Checa JC.  Cholesterol enrichment in liver mitochondria impairs oxidative phosphorylation and disrupts the assembly of respiratory supercomplexes.Redox Biology. 2019 Jun;24:101214.  doi: 10.1016/j.redox.2019.101214.   
  www.ncbi.nlm.nih.gov/pubmed/31108462
• López-Sánchez GN, Dóminguez-Pérez M, Uribe M,  Nuño-Lámbarri N. The fibrogenic process and the unleashing of acute-on-chronic liver failure. Clinical and Molecular Hepatology. 2019:14. doi: 10.3350/cmh.2019.0011.
  www.ncbi.nlm.nih.gov/pubmed/31195778
• Larenas-Linnemann D, Mullol J, Ivancevich JC, Anto JM, Cardona V, Dedeu T, et al. MASK (Mobile Airways Sentinel Network), a mobile App with ARIA's comprehensive solution in Spanish-speaking countries. Revista Alergia México. 2019;66(2):263-268. doi:10.29262/ram.v66i2.628
  www.ncbi.nlm.nih.gov/pubmed/31200425
• Larenas-Linnemann D,  Luna-Pech JA, Rodríguez-Pérez N, Rodríguez-González M, Arias-Cruz A, Blandón-Vijil MV,  et al. GUIMIT 2019, Mexican Guideline on Immunotherapy. Guideline on the diagnosis of IgE-mediated allergic disease and immunotherapy following the ADAPTE approach.  Revista Alergia México. 66 Suppl 1:1-105. doi: 10.29262/ram.v66i5.631.
  www.ncbi.nlm.nih.gov/pubmed/31200597
• Salva-Pastor N, Chávez-Tapia NC, Uribe M, Nuño-Lámbarri N. Understanding the association of polycystic ovary syndrome and non-alcoholic fatty liver disease. Journal of Steroid Biochemistry and Molecular Biology. 2019;194:105445 doi: 10.1016/j.jsbmb.2019.105445. www.ncbi.nlm.nih.gov/pubmed/31381969
• Bousquet J, Ansotegui IJ, Anto JM, Arnavielhe S, Bachert C, Basagaña X, Bédard A, Bedbrook A, Bonini M, Bosnic-Anticevich S, Braido F, Cardona V, Czarlewski W, Cruz AA, Demoly P, De Vries G, Dramburg S, Mathieu-Dupas E, Erhola M, Fokkens WJ, Fonseca JA, Haahtela T, Hellings PW, Illario M, Ivancevich JC, Jormanainen V, Klimek L, Kuna P, Kvedariene V, Laune D,  Larenas-Linnemann D, et al. Mobile Technology in Allergic Rhinitis: Evolution in Management or Revolution in Health and Care? Journal of Allergy and Clinical Immunology: In Practice. 2019: S2213-2198(19)30721-4.
   www.ncbi.nlm.nih.gov/pubmed/31445223
• Chávez-Tapia N. The bidirectional relationship between viral hepatitis infections and work. Annals of Hepatology. 2019;18(5):655. doi: 10.1016/j.aohep.2019.07.001 www.ncbi.nlm.nih.gov/pubmed/31416707
• Poitevin-Chacón MA. Discurso de ingreso de nuevos académicos numerarios a la Academia Nacional de Medicina de México, 2019. Gac Med Mex. 2019;155(4):448-449. www.ncbi.nlm.nih.gov/pubmed/31486793
• …Cruz AA, Czarlewski W, Durham S, Ebisawa M, Erhola M, Fauquert JL, Fokkens WJ, Fonseca JA, Guldemond N, Iinuma T, Illario M, Klimek L, Kuna P, Kvedariene V, Larenas-Linneman D, et al. Next-generation care pathways for allergic rhinitis and asthma multimorbidity: a model for multimorbid non-communicable diseases-Meeting Report (Part 1). Thorac Dis. 2019 Aug;11(8):3633-3642. doi: 10.21037/jtd.2019.08.64. www.ncbi.nlm.nih.gov/pubmed/31559071.
• …Bosse I, Boulet LP, Bourrez JM, Brusselle G, Chavannes N, Costa E, Cruz AA, Czarlewski W, Fokkens WJ, Fonseca JA, Gaga M, Haahtela T, Illario M, Klimek L, Kuna P, Kvedariene V, Le LTT, Larenas-Linnemann D, et al. Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases. Clin Transl Allergy. 2019 Sep 9;9:44. doi: 10.1186/s13601-019-0279-2. www.ncbi.nlm.nih.gov/pubmed/31516692
• …Cash E, Cecchi L, Chu DK, Colgan E, Costa E, Cruz AA, Czarlewski W, Durham S, Ebisawa M, Erhola M, Fauquert JL, Fokkens WJ, Fonseca JA, Guldemond N, Iinuma T, Illario M, Klimek L, Kuna P, Kvedariene V, Larenas-Linneman D, et al. Next-generation care pathways for allergic rhinitis and asthma multimorbidity: a model for multimorbid non-communicable diseases-Meeting Report (Part 2). J Thorac Dis. 2019 Sep;11(9):4072-4084. doi: 10.21037/jtd.2019.09.38. www.ncbi.nlm.nih.gov/pubmed/31656683
• Haahtela T, Halken S, Ierodiakonou D, Iinuma T, Ivancevich JC, Jutel M, Kaidashev I, Khaitov M, Kalayci O, Kleine Tebbe J, Kowalski ML, Kuna P, Kvedariene V, La Grutta S, Larenas-Linemann D, et al. Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence. J Allergy Clin Immunol. 2020 Jan;145(1):70-80.e3. doi: 10.1016/j.jaci.2019.06.049

  www.ncbi.nlm.nih.gov/pubmed/31627910

• Varela-Santoyo E, Escamilla-López MI, Izquierdo-Tolosa CD, Arroyave-Ramírez AM, Buerba-Vieregge HH, Dorantes-Heredia R, Motola-Kuba D, Ruiz-Morales JM. Impact of the Type of Analgesic Therapy on Postsurgical Complications of Patients with Kidney Cancer Undergoing Nephrectomy. Oncology. 2020;98(2):117-122. doi: 10.1159/000504258. www.ncbi.nlm.nih.gov/pubmed/31715614
• Larenas-Linnemann D, Romero-Tapia SJ, Virgen C, Mallol J, Baeza Bacab MA, García-Marcos L. Risk factors for wheezing in primary health care settings in the tropics. Ann Allergy Asthma Immunol. 2019 Nov 15. pii: S1081-1206(19)31388-2. doi: 10.1016/j.anai.2019.11.008. www.ncbi.nlm.nih.gov/pubmed/31734332
• Juárez-Hernández E, Uribe M. The lack of guidelines and government policies for regulating nonprescription sale of antibiotics and its medical consequences. Ann Hepatol. 2019;18(6):783-785. doi: 10.1016/j.aohep.2019.10.001. www.ncbi.nlm.nih.gov/pubmed/31735347
• Salva-Pastor N, Chávez-Tapia NC, Uribe M, Nuño-Lámbarri N. The diagnostic and initial approach of the patient with non-alcoholic fatty liver disease: role of the primary care provider. Gastroenterol Hepatol Bed Bench. 2019 Fall;12(4):267-277  www.ncbi.nlm.nih.gov/pubmed/31749914
• Désirée LL, Margarita FV, Mónica RG, María Del Carmen CS, Jorge Agustín LP, José Antonio OM, Blanca DR, Erika Del Carmen LE, Jade RL, Juan Carlos VG, Jorge SP. An online survey detected knowledge gaps and cost-saving opportunities in asthma maintenance treatment among allergists, pulmonologists, ENTs and primary care. World Allergy Organ J. 2019 Nov 19;12(12):100084. doi: 10.1016/j.waojou.2019.100084. www.ncbi.nlm.nih.gov/pubmed/31768217